Tian Zhonggeng, the winner of the 2002 Nobel Prize in Chemistry in Japan, announced that his research team has developed a new technology that can increase the sensitivity of current blood tests by 100 times. This new technology can detect cancer, lifestyle-related diseases and other diseases from a single drop of blood. It is of epoch-making significance to the early diagnosis and development of therapeutic drugs.
Under normal circumstances, if the human body does not have the protein "antigen" to invade, the human body will combine it to create an immune antibody "antibody" that attacks foreign antigens. The antibody has a "Y" shape and one of its two branches binds to the antigen. Tanaka’s research team artificially changed the structure of the antibody and implanted the elastic polymer compound polyethylene glycol at the root of the “Y†shape to make it soft like a spring. Both branches can bind to the antigen at the same time.
The team used a fragment of Alzheimer's disease-associated protein as an antigen and tested it with newly developed antibodies. The sensitivity of the antigen was found to be more than 100 times that of normal antibodies.
This new technology can find disease-related antibodies from more than 100,000 proteins and use a drop of blood to check for various diseases. Related results were published on the electronic version of the English Science Journal issued by the Japanese Academy of Education on the 11th.
Under normal circumstances, if the human body does not have the protein "antigen" to invade, the human body will combine it to create an immune antibody "antibody" that attacks foreign antigens. The antibody has a "Y" shape and one of its two branches binds to the antigen. Tanaka’s research team artificially changed the structure of the antibody and implanted the elastic polymer compound polyethylene glycol at the root of the “Y†shape to make it soft like a spring. Both branches can bind to the antigen at the same time.
The team used a fragment of Alzheimer's disease-associated protein as an antigen and tested it with newly developed antibodies. The sensitivity of the antigen was found to be more than 100 times that of normal antibodies.
This new technology can find disease-related antibodies from more than 100,000 proteins and use a drop of blood to check for various diseases. Related results were published on the electronic version of the English Science Journal issued by the Japanese Academy of Education on the 11th.
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